PCOS:-

What is PCOS ?

Polycystic ovarian syndrome is a problem caused by having abnormal levels of certain hormones in woman’s body. In PCOS, ovaria are larger than normal and there are a series of underdeveloped follicles that appear in clumps. If these cysts cause a hormonal imbalance, a pattern of symptoms may develop, which is called syndrome. These symptoms are the difference between suffering from polycystic ovary syndrome and from polycystic ovaries. PCOS is the name given to a metabolic condition in which a woman will have symptoms that reflect imbalances in reproductive and other hormones.

What are the symptoms of PCOS ?

The symptoms of PCOS can vary from woman to woman and may include excessive weight gain, irregular or completely absent periods, ovarian cysts, excessive facial or body hair known as hirsutism, male pattern hair loss, obesity, acne, skin tags, high cholesterol levels, exhaustion or lack of mental alertness, depression, anxiety, decreased sex drive, excess male hormones and infertility.

What tests do I have to do to determine PCOS ?

The diagnostic criteria are not definitive for PCOS. There are a few tests that help confirm insulin resistance. A fasting insulin blood test and cholesterol panels [specifically triglycerides]. Testosterone, cortisol and DHEA should also be tested. A pelvic scan of ovaries should be done for knowing the number of visible cysts. No cysts does not confirm that one does not have PCOS. Treatment is usually ineffective pharmaceutically and is usually more effective if strategies are arrived at life style and reducing insulin.

Can surgery treat PCOS ?

The removal of ovarian cysts is an effective way to treat PCOS. Cysts on the ovaries are the result of hormone imbalance that begin with the production of too much insulin. This over abundance of insulin causes an increase in male hormones, which eventually create the cysts. Laproscopic ovarian drilling is effective treatment with 60-70% pregnancy rates.

Because there is no cure for PCOS, it needs to be managed to prevent problems. Treatment goals are based on your symptoms, whether or not you want to become pregnant and lowering your chances of getting heart disease and diabetes. Many women will need a combination of treatments to meet these goals.

1. Birth Control Pills :- For women who do not want to be pregnant and still control menstrual cycles, reduce male hormone levels and help clear acne. However symptoms return once the pill is stopped.
2. Diabetes medications :--Metformin [Glucophage] helps women with PCOS symptoms, it lowers testosterone production, controls blood glucose, abnormal hair growth will slow down, ovulation may return after a few months use, it will also decrease body mass index [BMI] and improve cholesterol levels.
3. Fertility medications:- lack of ovulation is usually seen in PCOS. This can be treated with the use of clomiphene citrate. Clomiphene citrate + Metformin is also used for ovulation stimulation . Another option is IVF with Gonadotropins treatment.
4. Surgery ovarian drilling is a surgery that brings on ovulation . it is used on some women who does not respond to fertility medicines. Laparoscopy is also another option.
5. Life style modifications :-many Women with PCOS are overweight or obese. Keeping a healthy weight by eating healthy foods and exercising is another way woman can manage PCOS. Even a 10 percent loss in body weight can restore a normal period and make a women’s cycle more regular

Does PCOS put women at risk for other health problems ?

Women with PCOS have greater chances of developing several serious, life threatening diseases, including type 2 diabetes, cardiovascular disease [CVD] and cancer. Getting your symptoms under control at earlier age can help to reduce the above complications.

How is PCOS & infertility related ?

PCOS is some times associated with infertility. The most likely cause of infertility is anovulation or lack of ovulation. Ovulation can be induced with ovulation drugs [clomid & metformin], by gonadotropins or correction of insulin resistance. Laproscopic Ovarian Drilling is done if medical line of treatment do not work. The final option for achieving pregnancy in patients with PCOS related infertility is IVF i.e Invitro Fertilization with Gonadotropins.